Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Apparent diagnostic performance characteristics of a perfect biomarker when an imperfect gold standard has 25% sensitivity and 100% specificity. (A) The apparent sensitivity and specificity. (B) The apparent AUC-ROC curve (solid line, under the assumption of conditional independence) with lower and upper bounds (dotted lines). Results are plotted for a range of true disease prevalence estimates.
