Table 1.
Epidemiological data and diversity among ST69, ST393 and ST405 clonal groups
| ST (N°) | Serotype | PFGE-type (Cluster) | Country (N° isolates) | Date | Origina | Source (N° isolates) | ESBL / AmpC | Antibiotic resistance profileb | Virulence gene profileb | Reference |
|---|---|---|---|---|---|---|---|---|---|---|
| 69 |
O11, O73, O77 |
69_1 (I) |
US (4), NW (1) |
1999-2002 |
H |
Urine (3), blood (2) |
|
(Cm), Sm, Su, (Te), Tp, Ts |
fimH,iha, iutA, kpsMTII, K5, traT, sat, (ompT), (fyuA), papA, papEF, papGII, papC,(papGIII), (iroN), (iss), (ireA) |
[20,21] |
| 69 |
O77 |
69_2 (I) |
SP (1) |
- |
H |
Urine |
- |
Sm, Su, Te, Tp, Ts |
fimH, iha, iutA, kpsMTII, K5, traT, sat, ompT, fyuA, papA, papEF, papGII, papC, papGIII |
[20] |
| 69 |
- |
69_3 (I) |
BR (1) |
- |
H, C |
- |
- |
(Ak), Cm, (Gm), (Km), (Nt), Sm, Su, (Tb), Te, Tp, Ts |
fimH, iha, iutA, kpsMTII, K5, traT, sat, ompT, fyuA, papA, papEF, papGII, papC |
[12,22] |
| NW (1) |
2006 |
Urine |
CMY-2 |
|||||||
| 69 |
- |
69_4 (I) |
PT (1) |
2007 |
H |
Urine |
- |
Cp, Na, Sm, Su, Tp, Ts |
fimH, iha, iutA, kpsMTII, K5, traT, sat, ompT, papEF, iroN, iss |
This study |
| 69 |
O17 |
69_5 (I) |
US (1) |
- |
H |
Blood |
- |
Cm, Sm, Su, Te, Tp, Ts |
fimH, iha, iutA, kpsMTII, K5, traT, sat, ompT, fyuA, papA, papEF, papGII, papC, papGIII |
[20] |
| 69 |
- |
69_6 (II) |
PT (2) |
2010 |
S |
- |
- |
Km, Sm, Su, Te, Tp, Ts |
fimH, kpsMTII, K5, traT, ompT, papA, papEF, papC, papGIII, bmaE, gafD, iroN, iss |
[23] |
| 69 |
- |
69_7 (II) |
NW (1) |
2002 |
A |
Poultry meat |
- |
Sm, Su, Te, Ts |
fimH, iutA, traT, ompT, papC, iroN, iss, tsh, ireA |
[21] |
| 393 |
O15 |
NAc |
US (1) |
1980 |
H |
- |
- |
- |
fimH, iha, iutA, kpsMTII, K5, sat, ompT, fyuA, papA, papEF, papGII, papC, papGIII, tsh |
[4] |
| 393 |
O15 |
NAd |
US (1) |
1998 |
H |
- |
- |
Cm, Gm, Km, Nt, Sm, Su, Tb, Te, Tp, Ts |
fimH, iha, iutA, kpsMTII, K5, sat, ompT, fyuA, papA, papEF, papGII, papC |
[4] |
| 393 |
O15 |
NAe |
US (1) |
1999 |
H |
- |
|
Cp, Km, Na, Sm, Su, Te, Tp, Ts |
fimH, iha, iutA, kpsMTII, K5, sat, fyuA, papA, papEF, papGII, papC, tsh, papGI |
[4] |
| 393 |
O15 |
NAe |
KO (1) |
2006-7 |
C |
Urine |
- |
Cp, Gm, Km, Na, Nt, Sm, Su, Tb, Te, Tp, Ts |
fimH, iha, iutA, kpsMTII, K5, K1, traT, sat, ompT, fyuA, papA, papEF, papGII, papC |
[9] |
| 393 |
O15 |
NAe |
FR (1) |
2006 |
F |
Feces |
- |
Cm, Cp, Gm, Km, Na, Nt, Sm, Su, Tb, Te, Tp, Ts |
fimH, iha, iutA, kpsMTII, K5, traT, sat, ompT, papA, papEF, papGII, papC, iss, tsh |
[24] |
| 393 |
O25 |
NA |
FR (1) |
2006 |
F |
Feces |
- |
Cp, Na, Sm, Su, Te, Tp, Ts |
fimH, iha, iutA, kpsMTII, K5, sat, ompT, fyuA, papA, papEF, papGII, papC, iss |
[24] |
| 393 |
O15 |
NAe |
FR (1) |
2006 |
F |
Feces |
- |
Cm, Cp, Gm, Km, Nt, Sm, Su, Tb, Te, Ts |
fimH, iha, iutA, kpsMTII, K5, K1, traT, sat, fyuA, papA, papEF, papGII, papC, iss, tsh |
[24] |
| 393 |
O15 |
NA |
SP (1) |
2002 |
C |
Urine |
CTX-M-14 |
Cp, Na, Sm, Su, Ts |
fimH, iha, iutA, kpsMTII, K5, sat, papA, papEF, papGII, papC, iss, tsh |
[25] |
| 393 |
O15 |
NAe |
KO (1) |
2006-7 |
C |
Urine |
- |
Cp, Km, Na, Sm, Su, Te, Tp, Ts |
fimH, iha, iutA, kpsMTII, K5, papEF, papGII, papC |
[9] |
| 393 |
O15 |
NAe |
NW (1) |
2005 |
H |
Urine |
CMY-2 |
Cp, Km, Na, Nf, Sm, Su, Tp, Ts |
fimH, iutA, kpsMTII, K5, K1, ompT, fyuA, iss, tsh |
[12] |
| 2321 |
O25 |
NAe |
PT (1) |
2008 |
H |
Urine |
TEM-like |
Cp, Na, Sm, Su, Te, Tp, Ts |
fimH, iha, iutA, kpsMTII, K5, K1, sat, fyuA, papGII, papC, papGIII, iss, tsh, malX, iroN |
This study |
| 405 |
- |
405_1 (I) |
SP (1), KU (1)f NW (1) |
2002-2004 |
H |
Wound (1) Urine (1) Respiratory (1) |
CTX-M-15 (2), CTX-M-3 (1) |
(Cp), Cm, Gm, Km, Na, (Nt), Sm, Su, Tb, Te, Tp, Ts |
FimH, (iha), iutA, (kpsMTII), traT, sat, (malX), fyuA, (kpsMTIII), (iss), (tsh) |
[2,12] |
| 405 |
- |
405_2 (I) |
NW (1) |
2003 |
H |
Wound |
CTX-M-14 |
Cm, Km, Sm, Su, Te, Tp, Ts |
fimH, traT, malX, fyuA, kpsMTIII |
[12] |
| 405 |
- |
405_3 (I) |
NW (1) PT (1) f |
2003-2006 |
H |
Abcess (1) Urine (1) |
CMY-2 (1) CTX-M-15 (1) |
(Gm), (Km), Na, Sm, Su, (Tb), Te, Tp, Ts |
fimH, (iha), iutA, (kpsMTII), traT, malX, fyuA, (papEF), (papGIII), (iroN), (iss), (tsh), (ireA) |
[2,12] |
| 405 |
- |
405_4 (II) |
SW (1) SP (1) |
2000-2005 |
H, C |
Urine (1) Blood (1) |
CTX-M-15 TEM-24 |
(Cm), Cp, (Gm), Km, Na, (Nt), Sm, Su, Te, Tb, Tp, Ts |
(fimH), (iutA), traT, malX, fyuA, kpsMTIII, (iss), (tsh) |
[2,26] |
| 405 |
- |
405_5 (II) |
SP (1) |
2001 |
H |
Wound |
TEM-52 |
Cm, Cp, Gm, Km, Na, Sm, Su, Tb, Te, Ts |
traT, fyuA, kpsMTIII |
This study |
| 405 |
- |
NA |
SP (1) |
2008 |
C |
Urine |
CTX-M-15 |
Ak, Cp, Gm, Na, Tb, Ts |
fimH, fyuA |
[27] |
| 964 | - | 405_7 (III) | NW (1) | 2003 | H | Respiratory | CTX-M-15 | Cm, CpGm, Km, Na, Nf, Sm, Su, Tb, Te, Tp, Ts, | fimH, traT, sat, fyuA, papEF | [12] |
aH Hospitalized humans (obtained from representative outbreaks), C Community acquired infections (obtained from representative outbreaks), F Healthy humans (feces), A Animals, S Ready-to-eat salads. b Variability among isolates is represented in parenthesis. cIsolates identified as biotype A, dIsolates identified as biotype B; eIsolates identified as biotype C. f Isolate considered ExPEC. ND Not determined, NA, Not applicable, Ak Amikacin, Cm Chloramphenicol, Cp Ciprofloxacin, Gm Gentamicin, Km Kanamycin, Na Nalidixic acid, Nt Netilmicin, Nf Nitrofurantoin, Sm Streptomycin, Su Sulphonamides, Tb Tobramycin, Te Tetracyclin, Tp Trimethoprim, Ts Trimethoprim-Sulfamethoxazole, Definitions: fimH (type 1 fimbriae), papA (P fimbriae major subunit, pyelonephritis-associated), papC (P fimbriae assembly), papEF (P fimbriae minor tip pilins), papG allele I (papG variant), papG allele II (papG variant, pyelonephritis-associated), papG allele III (P fimbriae adhesion, cystitis-associated), sfa/focDE (S and F1C fimbriae), bmaE (Blood group M-specific adhesin), gafD (glucosamine-specific adhesin), iha (iron-regulated-gene-homologue adhesion), sat (secreted autotransporter toxin), tsh (serine protease autotransporter), fyuA (yersiniabactin receptor) iutA (ferric aerobactin receptor), iroN (catecholate siderophore receptor), ireA (Iron-regulated element ), kpsMTII (group II capsular polysaccharide), kpsMTII K1 (variant K1), kpsMTII K5 (variant K5), kpsMTIII (group III capsular polysaccharide), traT (serum survival associated), iss (increased serum survival), usp (uropathogenic-specific protein), ompT (outer membrane protease), malX (pathogenicity-associated island marker.