Table 2.

Details of the quality of evidence categories in GRADE

GRADE	Descriptor
High	Further research is very unlikely to change our confidence in the estimate of effect
Moderate	Research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate
Low	Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate
Very low	Any estimate of effect is very uncertain.