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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Neuropharmacology. 2013 Feb 13;70:236–246. doi: 10.1016/j.neuropharm.2013.01.020

Figure 6. Pioglitazone inhibits expression of cd11b, GFAP, and p-p38.

Figure 6

Intraperitoneal saline or drug administration was started 15 min prior to SNI surgery. Injections continued twice daily on days 1–7. Pioglitazone reduced the staining for cd11 b (A,D,G), GFAP (B,E,H) and phosphorylated p38 (C,F,I) (n = 6 per group). Insets in the lower left panels (A–F) represent 10× magnification of the 100 µm square portion of the sural innervation territory lamina II-III. Values represent mean ± SEM. (★) denotes significant difference (p<0.05 vs. vehicle by post-hoc t-tests). Scale bar = 100µm.