Fig. 2.

Effects on antioxidant activity of a switch from PI, EX (voluntary wheel running), or CAT (30 mg/kg/day in drinking water) with a RD from the age of 1 to 9 months to PI and a WD from the age of 9 to 12 months. Oxidative stress was evaluated by quantifying in the aorta the activity of catalase (a, b, c; n=4–5), SOD2 (d, e, f; n=4–5), and GPx (g, h, i; n=4–6) and by measuring the circulating levels of isoprostane (j, k, l; n=3–5). Results are presented as the mean± SEM. ^#p<0.05 compared to 9 months of age (treatment matching group), *p<0.05 compared to 12 months of age with RD (treatment matching group), ^Pp<0.05 compared to PI, ^Ep<0.05 compared to EX, and ^Cp<0.05 compared to CAT