Table 1.
Body mass, plasma glucose, insulin, total cholesterol (TC), and SBP from PI, EX (voluntary wheel running), and CAT-treated (30 mg/kg/day in drinking water) mice from 1 to 9 months of age fed with a RD (9 months) and then maintained for 3 months in inactive conditions and fed either a RD (12 months) or a WD (12 months)
| Age/diets | 9 months RD
|
12 months RD
|
12 months WD
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Treatments | PI | EX | CAT | PI | EX | CAT | PI | EX | CAT | n |
| Body mass (g) | 30.4±1.3 | 32.4±1.2 | 31.1±1.2 | 33.4±1.6 | 35.7±1.9 | 31.0±0.8 | 44.9±1.5* | 43.9±1.6* | 45.5±0.9* | 9–15 |
| Glucose (mmol/L) | 17.5±1.1 | 15.9±1.7 | 19.2±0.8 | 16.4±0.9 | 20.0±1.9 | 15.7±0.8 | 22.3±0.8* | 19.5±2.6 | 20.5±1.9* | 4–7 |
| Insulin (ng/ml) | 0.17±0.04 | 0.27±0.06 | 0.19±0.06 | 0.29±0.09 | 0.23±0.08 | 0.21±0.05 | 0.49±0.12* | 0.57±0.18* | 0.44±0.11* | 8–10 |
| TC (mmol/L) | 2.4±0.1 | 2.8±0.1 | 2.8±0.1 | 2.6±0.1 | 2.6±0.3 | 2.9±0.1 | 6.9±1.1* | 7.2±1.1* | 5.4±0.6* | 4–7 |
| SBP (mmHg) | 141.0±6.2 | 142.3±2.9 | 148.1±2.8 | 143.3±5.5 | 140.6±3.7 | 149.0±1.8 | 134.1±8.1 | 145.5±4.3 | 138.8±3.2 | 4–14 |
Results are presented as the mean±SEM
*
p<0.05 compared to 12 months RD (treatment matching group)