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. 2013 Jun 28;8(6):e67968. doi: 10.1371/journal.pone.0067968

Table 3. Summary of cell populations with “embryonic-like stem cell” features reported in the hUCB LinCD45 fraction.

Name Immunophenotype andtranscripts Isolation Morphology Survivaland Growth Specie(s)/Tissue PossibleFunction Reference
hUCB Lin CD45 population (non-HSC) LinCD45CD34+, LinCD45CXCR4+,LinCD45Nestin+, SSEA-4, SOX2, OCT4, NANOG, Hoescht +. Lysis, Magnetic Columns. 6–10 microns, Highnuclear/cytoplasmic ratio Human Cord Blood. Quiescent. This study
Very Small Embryonic-like stem cells (VSELs) CD34, CD133, CXCR4, SSEA-4, SOX2,OCT4, NANOG, CD31, Hoescht(low/−/+). Lysis, Magnetic Columns, FACS Sorting 3–7 microns, High nuclear/cytoplasmic ratio −/+ Human Cord Blood. Quiescent, Long-termrepopulation. [4], [5], [23], [32]
Cord-blood-derived embryonic-like stem cells (CBEs) SSEA-4, SOX2, OCT4, NANOG. Ficoll density, Magnetic Selection. 3–6 microns + Human Cord Blood Not reported [3], [7], [21]