Table 1. Demographic characteristics, anthropometric measurements, and concentrations of biomarkers in patients with premature AMI and healthy controls.
| Characteristics* | Patients | Controls | p value** |
| (n = 203) | (n = 205) | ||
| Gender, n(%) | |||
| Males | 146(71.9) | 148(72.2) | 0.95 |
| Females | 57(28.1) | 57(27.8) | 0.95 |
| Age(Years) | 41.6±4.5/43.0(5.0) | 41.3±4.7/42.0(5.0) | 0.51 |
| BMI, kg/m2 | 25.7±3.6/25.1(4.8) | 25.99±4.9/25.5(6.2) | 0.53 |
| Homocysteine, µmol/L | 23.2±17.4/18.6(9.5) | 23.45±18.6/18.6(9.1) | 0.78 |
| Serum folate, ng/mL | 6.92±3.77/5.7(4.6) | 6.89±3.72/6.1(4.8) | 0.94 |
| Serum vitamin B12, pg/mL | 315±188/276(230) | 364±180/331(230) | 0.007 |
| Blood lead, µg/dL | 16.3±6.94/14.6(9.5) | 14.4±7.7/12.7(8.3) | 0.011 |
| Ferritin, ng/mL | 158.7±136.7/128.9(141.9) | 87.1±74.7/66.7(86.8) | <0.001 |
| sTfR, µg/mL | 3.70±1.70/3.20(1.50) | 4.14±2.91/3.45(1.60) | 0.6 |
| sTfR/Ferritin | 84.7±295/28.9(38.4) | 255±836/49.4(83.8) | <0.001 |
| Total cholesterol, mg/dL | 152±46/150(63) | 171±34/170(47) | <0.001 |
| Triglycerides, mg/dL | 125±58/114(70) | 154±93/131(97) | <0.001 |
| LDL-cholesterol, mg/dL | 98±39/94(53) | 105±33/103(47) | 0.023 |
| HDL-cholesterol, mg/dL | 28.2±11.3/27.0(11.0) | 38.0±8.0/37.0(11.0) | <0.001 |
*
Values are mean±SD/median (IQR) except for gender which are presented as n(%).
**
p value was obtained by comparing mean±SD values using Independent sample t test, however, Mann-Whitney U test was used to compare distributions for variables homocysteine, ferritin, sTfR and sTfR/ferritin.
BMI = body mass index, sTfR = soluble transferrin receptor.