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. 2013 Jun 28;8(6):e65684. doi: 10.1371/journal.pone.0065684

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Sample size was 22 for the no stimulation group (data from first five sessions were pooled from all the groups which received stimulation during last five sessions), 6 for 20 Hz group, 8 for 50 Hz group and 8 for 100 Hz group. These groups (indicated by solid lines) were stimulated for 200 ms immediately following each successful response. In addition, we included a separate control group (indicated by dashed line, n = 8) which was stimulated at 20 Hz for 500 ms, i.e., the same frequency as the 20 Hz group but the same number of pulses as the 50 Hz group. Only the 50 and 100 Hz groups showed learning curves that were significantly different from the no-stimulation group after post hoc correction (p<.05).