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. 2013 Jun 28;8(6):e67135. doi: 10.1371/journal.pone.0067135

Figure 5. The proteolytic activity of Natterins is crucial for the maintenance of memory B cells in the spleen.

Figure 5

Total memory B cell (CD19pos in B220posIgGpos gated cells) numbers in peritoneum (A, D), spleen (B, E) and BM (C, F) was determined from total mononuclear cells by multiparametric flow cytometer using Armenian hamster IgG1y2 FITC-anti-mouse CD19, Goat IgG2bk PE-anti-mouse IgG (specific for IgG1, IgG2a, IgG2b and IgG3), Rat IgG2ak PerCP-Cy5-anti-mouse CD45R/B220. *p<0.05 compared to control-mice, and # p<0.05 compared to active Natterins.