Table 4. Multivariable Cox Model of risk factors for technical failure.

Factors identified in the univariable analysis were incorporated in a full multivariable Cox Model and verified in a reduced model. The predictive factors were assembled in a Composite Risk Model incorporating donor age, donor BMI, donor Cr, and preservation time and adjusted for surgical approach. Transplants with no risk factors were compared to those with one, two, or three risk factors. For comparison the pDRI risk categories were similarly modeled.

Full Model
	Hazard Ratio	LCL	UCL	p value
SPK Transplant	1.12	0.65	1.94	0.683
Bladder Drainage	0.52	0.30	0.88	0.015
Donor Age >50	2.05	1.01	4.18	0.047
Preservation Time >20 hours	2.07	1.31	3.29	0.002
Donor BMI ≥30	1.60	0.95	2.68	0.076
Cause of Death - Stroke	0.78	0.43	1.41	0.415
Cause of Death - Head Trauma	0.76	0.43	1.34	0.344
Social History - Alcohol Abuse	1.41	0.67	2.96	0.365
Elevated Creatinine (≥ 2.5)	3.10	1.21	7.93	0.018
Elevated Amylase (≥ 500)	1.50	0.54	4.16	0.438
Recipient BMI >30	1.40	0.79	2.49	0.251
Recpient Smoking History	0.97	0.48	1.97	0.940
Campath Induction	0.88	0.47	1.66	0.692
Reduced Model
	Hazard Ratio	LCL	UCL	p value
Bladder Drainage	0.54	0.36	0.80	0.002
Donor Age >50	1.73	0.93	3.19	0.082
Preservation Time >20 hours	2.17	1.45	3.23	<0.001
Donor BMI ≥30	1.87	1.21	2.88	0.005
Elevated Creatinine (≥ 2.5)	3.16	1.37	7.26	0.007
Composite Model
	Hazard Ratio	LCL	UCL	p value
Bladder Drainage	0.61	0.42	0.88	0.009
Risk Factors
No Risk Factors (n = 519)	1.00
1 Risk Factor (n = 377)	1.35	0.80	1.91	0.346
2 Risk Factors (n = 87)	3.65	2.20	6.06	< 0.001
3 Risk Factors (n= 14)	7.66	3.26	18.04	< 0.001
pDRI Model
	Hazard Ratio	LCL	UCL	p value
Bladder Drainage	0.67	0.46	0.97	0.036
pDRI Quintiles
First	1.00
Second	1.01	0.46	2.23	0.980
Third	1.56	0.70	3.50	0.276
Fourth	2.53	1.16	5.48	0.019
Fifth	3.15	1.39	7.11	0.006