Table 1.
Summary characteristics for study cohort and by CD4 cell count at enrollment
| Total Cohort (n=473) | CD4<250 cells/μL (n=413) | CD4≥250 cells/μL (n=60) | p-value‡ | |
|---|---|---|---|---|
| Baseline Characteristics | ||||
| Age (median, IQR) | 34 (29-39) | 34 (29-39) | 36 (29-41) | 0.72 |
| Female (%) | 70.6 | 70.5 | 71.7 | 0.85 |
| Married (%) | 42.7 | 42.2 | 48.3 | 0.38 |
| Achieved Secondary Education or Greater (%) | 25.0 | 26.3 | 18.6 | 0.21 |
| Unemployed (%) | 26.0 | 26.0 | 26.7 | 0.91 |
| Asset Index (Median, IQR) | -0.5 (-1.6 to 0.9) | -0.3 (-1.5 to 1.0) | -0.8 (-1.8 to 0.6) | 0.21 |
| Distance to Clinic in minutes (Median, IQR) | 40 (30 – 60) | 33 (30 – 60) | 43 (20 – 60) | 0.71 |
| Depression (%) (HSCL >1.75) | 35.7 | 35.9 | 36.7 | 0.91 |
| Audit-C Screen Positive (%) | 20.7 | 22.3 | 16.1 | 0.29 |
| Physical Health Summary Score (Median, IQR) | 40.4 (31.1 – 49.0) | 39.6 (30.2 – 48.5) | 44.9 (39.1 – 51.6) | 0.01 |
| Daily ARV Dosing (%) | 47.6 | 47.5 | 50.9 | 0.63 |
| CD4 Cell Count (median, IQR) | 132 (76 – 200) | 119 (65-168) | 327 (275 – 400) | |
| Log10 HIV Viral Load at baseline (mean, range) | 5.0 (1.6 – 7.0) | 5.1 (1.6 – 7.0) | 4.6 (1.6 – 6.7) | <0.01 |
| Follow-Up Data | ||||
| Average Adherence (%) | 89.0 | 89.4 | 85.7 | 0.08 |
| HIV Viral Load >400 copies/ml at follow-up visit | 10.6 | 9.5 | 19.0 | 0.06 |
| Deaths (n, %) | 17 (3.6%) | 15 (3.6%) | 2 (3.3%) | 0.91 |
| Lost to follow up (n, %) | 31 (6.8%) | 26 (6.5%) | 5 (8.6%) | 0.56 |
‡
Tests of association between the two exposure groups (CD4 cell count <250 and CD4 cell count ≥250 cells/μL) were performed using chi-squared testing for categorical variables and non-parametric ranksum testing for continuous, non-normally distributed variables