Table 3. Association between baseline sterol levels and glucose area under the curve (AUC) at the 5-year follow-up study.
| Sterol, adjusted for total cholesterol | B (SE) | P | P* | P† | P‡ |
| Synthesis markers | |||||
| Squalene | 15.8 (54.1) | 0.871 | 0.723 | 0.124 | 0.803 |
| Lathosterol | 142.8 (47.0) | 0.002 | 0.140 | 0.879 | 0.259 |
| Cholestenol | 240.0 (56.0) | 1.1E-05 | 6.5E-04 | 0.041 | 0.003 |
| Desmosterol | 376.7 (80.0) | 4.2E-07 | 1.6E-04 | 0.256 | 0.193 |
| Absorption markers | |||||
| Cholestanol | −280.9 (92.1) | 0.002 | 0.065 | 0.617 | 0.051 |
| Campesterol | −209.3 (42.2) | 1.7E-07 | 0.003 | 0.151 | 0.043 |
| Sitosterol | −214.0 (41.0) | 6.6E-08 | 0.002 | 0.049 | 0.037 |
| Avenasterol | −322.8 (64.6) | 1.7E-07 | 0.006 | 0.038 | 0.052 |
Linear regression analysis, adjusted for age, BMI, smoking, physical activity and additional covariates as listed below. Individuals with previously diagnosed diabetes or with statin or ezetimibe treatment were excluded (N = 458–474). B, unstandardized beta, SE, standard error. Bold types indicate statistical significance with P≤0.006.
P, unadjusted.
P*, adjusted for age, BMI, smoking, and physical activity.
P†, adjusted for age, BMI, smoking, physical activity and Matsuda ISI.
P‡, adjusted for age, BMI, smoking, physical activity, Matsuda ISI, InsAUC0–30/GluAUC0–30, glucose AUC at baseline and total triglycerides.