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Antihyperglycaemic action of tetrahydrocyclopropa[a]indene glucokinase activators after acute oral administration in db/db mice. Data are means ± SEM of 10 animals. *P < 0.05, **P < 0.01, ***P < 0.001 significantly different from vehicle; Dunnett's t-test. FFA, free fatty acid; TG, triglyceride.
