Table 5.
Allelic association test for SNPs
| SNP | Control (n = 320) | Non-PCD (n = 170) | PCD (n = 147) | p value |
|---|---|---|---|---|
| NOD2 | ||||
| NOD2 1007insC | ||||
| N | 602 (98.4) | 295 (92.2) | 266 (94.3) | <0.0011 |
| C | 10 (1.6) | 25 (7.8) | 16 (5.7) | <0.0012 |
| 0.2993 | ||||
| NOD2 R702W | ||||
| C | 517 (97.2) | 288 (88.9) | 254 (90.1) | <0.0011 |
| T | 15 (2.8) | 36 (11.1) | 28 (9.9) | <0.0012 |
| 0.6373 | ||||
| NOD2 G908R | ||||
| C | 618 (99.0) | 319 (95.5) | 272 (96.5) | 0.0021 |
| G | 6 (1.0) | 15 (4.5) | 10 (3.5) | <0.0012 |
| 0.5543 | ||||
| IL-23r | ||||
| rs1004819 | ||||
| G | 381 (72.7) | 203 (64.6) | 164 (60.3) | <0.0011 |
| A | 143 (27.3) | 111 (35.4) | 108 (39.7) | 0.0142 |
| 0.2773 | ||||
| rs10489629 | ||||
| T | 335 (56.0) | 180 (58.8) | 177 (63.2) | 0.1291 |
| C | 263 (44.0) | 126 (41.2) | 103 (36.8) | 0.4202 |
| 0.2773 | ||||
| rs2201841 | ||||
| C | 433 (71.7) | 213 (66.1) | 169 (61.7) | 0.0101 |
| G | 171 (28.3) | 109 (33.9) | 105 (38.3) | 0.0802 |
| 0.2573 | ||||
| rs11465804 | ||||
| T | 586 (94.5) | 329 (97.9) | 285 (97.6) | 0.0111 |
| G | 34 (5.5) | 7 (2.1) | 7 (2.4) | 0.0132 |
| 0.7903 | ||||
| rs11209026 | ||||
| G | 544 (96.5) | 310 (97.5) | 266 (98.5) | 0.2241 |
| A | 20 (3.5) | 8 (2.5) | 4 (1.5) | 0.4022 |
| 0.3773 | ||||
| IGR | ||||
| rs2522057-2060 | ||||
| C | 300 (55.6) | 137 (49.3) | 118 (49.2) | 0.1201 |
| G | 240 (44.4) | 141 (50.7) | 122 (50.8) | 0.0882 |
| 0.9793 | ||||
| rs7705189-3096 | ||||
| A | 319 (52.0) | 159 (48.8) | 130 (48.1) | 0.4781 |
| G | 295 (48.0) | 167 (51.2) | 140 (51.9) | 0.3532 |
| 0.8793 | ||||
| OCTN1 | ||||
| rs1050152 | ||||
| C | 364 (56.9) | 166 (51.2) | 132 (48.9) | 0.0521 |
| T | 276 (43.1) | 158 (48.8) | 138 (51.1) | 0.0962 |
| 0.5693 | ||||
Figures in parentheses indicate percentages. Under each studied SNP in the table, the top row correlates with the major allele distribution while the bottom row correlates with the minor allele distribution in the studied group.
Global p value among all groups.
Control vs. non-PCD.
Non-PCD vs. PCD.