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. 2012 Mar 22;29(2):107–114. doi: 10.1159/000335745

Table 5.

Allelic association test for SNPs

SNP Control (n = 320) Non-PCD (n = 170) PCD (n = 147) p value
NOD2
NOD2 1007insC
 N 602 (98.4) 295 (92.2) 266 (94.3) <0.0011
 C 10 (1.6) 25 (7.8) 16 (5.7) <0.0012
0.2993
NOD2 R702W
 C 517 (97.2) 288 (88.9) 254 (90.1) <0.0011
 T 15 (2.8) 36 (11.1) 28 (9.9) <0.0012
0.6373
NOD2 G908R
 C 618 (99.0) 319 (95.5) 272 (96.5) 0.0021
 G 6 (1.0) 15 (4.5) 10 (3.5) <0.0012
0.5543

IL-23r
rs1004819
 G 381 (72.7) 203 (64.6) 164 (60.3) <0.0011
 A 143 (27.3) 111 (35.4) 108 (39.7) 0.0142
0.2773
rs10489629
 T 335 (56.0) 180 (58.8) 177 (63.2) 0.1291
 C 263 (44.0) 126 (41.2) 103 (36.8) 0.4202
0.2773
rs2201841
 C 433 (71.7) 213 (66.1) 169 (61.7) 0.0101
 G 171 (28.3) 109 (33.9) 105 (38.3) 0.0802
0.2573
rs11465804
 T 586 (94.5) 329 (97.9) 285 (97.6) 0.0111
 G 34 (5.5) 7 (2.1) 7 (2.4) 0.0132
0.7903
rs11209026
 G 544 (96.5) 310 (97.5) 266 (98.5) 0.2241
 A 20 (3.5) 8 (2.5) 4 (1.5) 0.4022
0.3773

IGR
rs2522057-2060
 C 300 (55.6) 137 (49.3) 118 (49.2) 0.1201
 G 240 (44.4) 141 (50.7) 122 (50.8) 0.0882
0.9793
rs7705189-3096
 A 319 (52.0) 159 (48.8) 130 (48.1) 0.4781
 G 295 (48.0) 167 (51.2) 140 (51.9) 0.3532
0.8793

OCTN1
rs1050152
 C 364 (56.9) 166 (51.2) 132 (48.9) 0.0521
 T 276 (43.1) 158 (48.8) 138 (51.1) 0.0962
0.5693

Figures in parentheses indicate percentages. Under each studied SNP in the table, the top row correlates with the major allele distribution while the bottom row correlates with the minor allele distribution in the studied group.

1

Global p value among all groups.

2

Control vs. non-PCD.

3

Non-PCD vs. PCD.