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Effect of IGF-I gene therapy on PRL, GH and TSH cell populations of pituitary adenomas. Representative fields of specifically immunostained cells from the pituitary gland of an intact rat, an animal which received estrogen for 4 weeks and RAd-GFP during the last experimental week (E2 + RAd-GFP) and an animal which received estrogen for 4 weeks and RAd-IGF-I during the last experimental week (E2 + RAd-IGF-I). Envision system peroxidase. Bar = 45 μm.
