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. 2001 Apr 15;107(8):985–993. doi: 10.1172/JCI10734

Figure 4.

Figure 4

Cha autoantibodies in experimental T cruzi infections. (a) Reactivity against rsCha of sera from five mice infected with the Tulahuen and five infected with the MC strains of T. cruzi at different days after infection. Seen are values of individual mice (open circles) and mean of OD values of all mice (filled circles). Parasitemia values are expressed as trypomastigotes (10–5/ml) (filled triangles). (b) Mapping of the sCha epitope recognized by infected mice sera. T. cruzi–infected mice sera against ten-aa overlapping peptides spanning sCha were assayed. Reactivity of uninfected sera (filled diamonds) 21 days after infection (filled squares) and 53 days after infection (filled circles). Reactivity of the same sera against the S1 peptide of T. cruzi and R1 peptide of Cha is seen.