. Author manuscript; available in PMC: 2014 Feb 28.

Published in final edited form as: J Cyst Fibros. 2012 Sep 1;12(2):147–153. doi: 10.1016/j.jcf.2012.08.001

Table 1.

Frequency and diagnostic properties of individual and combined ELISAs.

P.aeruginosa		Culture		Sensitivity	Specificity	PPV ^a	NPV ^b	Concordance ^c
Antigen		−	+
Alkaline protease ^d	−	633	109	0.45	0.81	0.38	0.85	0.74
	+	144	89
Elastase ^d	−	608	95	0.52	0.78	0.38	0.86	0.73
	+	169	103
Exotoxin A ^d	−	449	65	0.67	0.58	0.29	0.87	0.60
	+	328	133
PopB+ExoS ^e	−	647	102	0.48	0.83	0.42	0.86	0.76
	+	130	96
PAO1 cell lysate ^e	−	560	79	0.60	0.72	0.35	0.88	0.70
	+	217	119
Exotoxin A ^a	−	716	146	0.26	0.92	0.46	0.83	0.79
	+	61	52
E-15 combined ^d	−	371	44	0.78	0.48	0.28	0.89	0.54
	+	406	154
MCW combined ^e	−	502	61	0.69	0.65	0.33	0.89	0.66
	+	275	137

PPV refers to positive predictive value.

NPV refers to negative predictive value.

Concordance is the proportion of all 975 samples that were culture negative/seronegative or culture positive/seropositive.

Component of Mediagnost^® E-15 ELISA kit (Reutlingen, Germany).

Studies conducted at Dr. Joseph Barbieri’s laboratory, Medical College of Wisconsin.