Table 2.
Laboratory outcomes of 134 IVM cycles in NO and PCOS patients. An AMH threshold of 1.6 ng/ml was identified for obtaining at least 5 matured oocytes
| Normo-ovulatory | PCOS | ||||
|---|---|---|---|---|---|
| AMH < 1.6 ng/ml | AMH > 1.6 ng/ml | P | (n = 20/30) | P | |
| (n = 37/55) | (n = 43/49) | ||||
| Mean serum AMH level (ng/ml) | 0.8 ± 0.4 | 3.2 ± 1 | 0.001 | 8.5 ± 4 | 0.001 |
| Total no. of oocytes retrieved | 200 | 472 | 491 | ||
| Mean no. of oocyte at OPU | 3.7 ± 2.3 | 9 ± 5.5 | 0.001 | 15 ± 9 | 0.001 |
| Mean no. of matured oocytes at OPU: | 0.66 ± 1 | 0.76 ± 1.2 | NS | 1.4 ± 1.7 | 0.01 |
| Maturational rate (OPU) | 0.2 ± 0.3 | 0.1 ± 0.1 | 0.01 | 0.1 ± 0.1 | NS |
| Mean no. Of matured oocytes oocytes (24 h)a | 1.1 ± 1.3 | 2.8 ± 2.7 | 0.001 | 4.2 ± 3 | 0.001 |
| Maturational rate (24 h) | 0.5 ± 0.3 | 0.37 ± 0.3 | NS | 0.36 ± 0.2 | NS |
| Mean no. Of matured oocytes (48 h)b | 0.8 ± 1.1 | 1.6 ± 2.15 | 0.001 | 2.3 ± 3.2 | 0.01 |
| Maturational rate (48 h) | 0.7 ± 0.2 | 0.5 ± 0.2 | NS | 0.5 ± 0.2 | NS |
| Mean final no. of matured oocytes: | 2.5 ± 1.9 | 5.3 ± 4.2 | 0.001 | 7.7 ± 5 | 0.01 |
| Final maturational rate | 0.7 ± 0.3 | 0.55 ± 0.28 | NS | 0.5 ± 0.2 | NS |
| Mean no. of 2PN | 2.2 ± 1.5 | 3.5 ± 2.6 | 0.005 | 5.5 ± 2.8 | 0.01 |
| Fertilization rate | 0.6 ± 0.3 | 0.7 ± 0.2 | NS | 0.74 ± 0.2 | NS |
| No. of cryo-preserved embryos | 1.4 ± 0.7 | 4.1 ± 3.1 | 0.001 | 3.6 ± 2.2 | 0.01 |
| ET | 2.3 ± 1.1 | 2 ± 0.8 | NS | 2.6 ± 0.7 | NS |
| Total Embryo no. | 1.4 ± 1.4 | 2.3 ± 2.8 | 0.0001 | 3.6 ± 2.2 | 0.01 |
Values given as mean ± St. Dev.
ET embryos transfer
aMean no. of oocytes that completed their maturation in the first 24 following OPU (M2 oocytes on OPU day are excluded)
bMean no. of oocytes that completed their maturation between 24 and 48 h following OPU (M2 oocytes of the first 24 h are excluded)