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. Author manuscript; available in PMC: 2013 Jun 30.
Published in final edited form as: Neuropsychopharmacology. 2007 Nov 7;33(6):1239–1251. doi: 10.1038/sj.npp.1301528

Figure 4. SERT and 5HT2AR Binding Potentials (BPs) in TS+OCD and TS−OCD Subjects, and Normal Controls.

Figure 4

Panel A: Significant reductions (p < 0.05) were seen in serotonin transporter (SERT) BP in the midbrain, caudate, and putamen of subjects with Tourette syndrome (TS), when compared with normal controls. Panel C: No significant differences were seen in serotonin receptor (5-HT2AR) BP between TS and normal controls (p > 0.05). Panel B: When grouped by OCD status, the TS+OCD groups displayed significant decreases in SERT BP in midbrain, as compared with normal controls (p < 0.05). Panel D: When grouped by OCD status, TS+OCD subjects showed slightly higher 5-HT2A binding, but these results were not significant (p>0.1).