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. Author manuscript; available in PMC: 2013 Jun 30.
Published in final edited form as: Expert Rev Mol Diagn. 2013 Apr;13(3):257–269. doi: 10.1586/erm.13.15

Figure 3. Prodrug constructs and hypothetical pathway of prodrug activation.

Figure 3

The development of a prodrug/activatable therapy (A–E) and the functional pathway (F) upon which the drug is activated inside the cell by the target protease. Reproduced with permission from [71].