Skip to main content
. 2013 Jun 20;3(3):323–338.

Figure 2.

Figure 2

Analyses of plasma rigosertib pharmacokinetics. A. Cmax vs. Dose levels. B. AUC0-∞ vs. Dose levels. C. Clearance vs. Dose levels. Dose levels with >3 data points were shown as mean ± SD, dose levels with 2 data points were shown as mean ± the range. The least square regression line was drawn. Correlation coefficient values calculated by Excel “correl” function were: Dose vs. Cmax: 0.962; Dose vs. AUC0-∞: 0.921 and Dose vs. Clearance: 0.521. PK values of 3 patients who experienced SAEs and DLTs are shown in red marks.