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The p21 expression induction in individual genetic groups. Medians of p21 expression and the significance (Kruskal-Wallis ANOVA test) related to wt group were following: (A) after doxorubicin treatment – wt: 815%; del-ATM: 731%; non-significant (NS); mut-ATM: 182%, P<0.001; def-TP53: 250%, P<0.001. (B) after fludarabine treatment – wt: 718%; del-ATM: 639%, NS; mut-ATM: 617%, NS; def-TP53: 190%, P<0.001.
