Surface plasmon resonance analysis of GDH interactions.
A–D, interaction of GDH with core histones was analyzed by SPR-recombinant histone H3 (A), H2A (B), H2B (C), and H4 (D). E, binding kinetics of GDH is shown. The Kd, kon, and koff rate contants for the GDH-H3, GDH-H2A, GDH-H2B, and GDH-H4 interactions are shown.