Table 1.

Untargeted serum proteomic analysis in human UC: Up- and down-regulated proteins

Uniprot suggested name	Fold-change (increase or decrease)	UniProtKB	%Coverage	%Coverage(95%)	Peptides(95%)
	Increase
Serum Amyloid A	11.7	P02735	85.3	35.2	4
α-1-Antichymotrypsin (SERPINA3)	4.2	P01011	63.8	17.3	8
Haptoglobin	2.6	P00738	86.9	56.4	50
α-1-Acid glycoprotein 1 (Orosomucoid 1)	2.5	P02763	74.1	36.3	12
α-1-Antitrypsin (SERPINA1)	2.3	P01009	82.1	60.3	52
Leucine-rich α-2-glycoprotein	1.9	P02750	55.0	8.1	3
Peptidoglycan recognition protein 2	1.7	Q96PD5	35.1	2.4	1
Plasma protease C1 inhibitor (SERPING1)	1.5	P05155	53.0	14.2	10
β-2-glycoprotein 1	1.5	P02749	63.5	11.6	4
Hemopexin	1.4	P02790	58.9	25.1	15
α-1-Acid glycoprotein 2 (Orosomucoid 2)	1.3	P19652	74.6	22.4	6
Complement factor H	1.3	P08603	50.7	9.2	11
Vitronectin	1.3	P04004	54.4	13.0	7
Heparin cofactor 2 (SERPIND1)	1.3	P05546	50.9	8.8	5
Complement factor B	1.3	P04186	51.4	13.3	12
α-1B-glycoprotein	1.3	P04217	53.3	17.2	7
	Decrease
Transferrin	0.7	P02787	87.4	63.7	93
Tissue-type plasminogen activator	0.7	P00750	46.8	10.4	7
α-2-HS-glycoprotein	0.7	P02765	49.9	20.4	5
Interα-trypsin inhibitor heavy chain H2	0.7	P19823	47.7	4.3	3
Retinol-binding protein 4	0.6	P02753	59.7	10.5	3
Hemoglobin subunit-β	0.6	P68871	87.1	43.5	6
Apolipoprotein A-II	0.5	P02652	80.0	41.0	10
Apolipoprotein A-I	0.5	P02647	94.0	69.7	46
α-2-Macroglobulin	0.5	P01023	76.5	47.7	90