Skip to main content
. 2013 Jun 12;110(26):10765–10770. doi: 10.1073/pnas.1301693110

Fig. 1.

Fig. 1.

Members of the miR-17∼92 miRNA cluster are up-regulated in mouse models of PKD. (A) qRT-PCR analysis showing increased expression of miRNAs derived from the miR-17∼92 cluster in kidneys from 28-d-old Kif3a-KO mice compared with control mice. (B–D) Expression of the miR-17∼92 cluster is also increased in kidneys from Pkhd1/cre;Hnf-1βF/F mice (B), Pkhd1/cre;Pkd2F/F mice (C), and Pkhd1−/− mice (D) compared with kidneys from their respective controls. *P < 0.05, **P < 0.01, and #P > 0.05. Error bars represent SEM.