Fig. 2.

Extended Drosophila genetic subnetwork. The subnetwork of proteins connected to Smn and its genetic modifiers in the DPiM. A total of 62 Smn genetic modifiers (diamonds with red border) are directly connected to 361 other proteins (circles), also known as first-degree neighbors through 3,800 interactions. The thickness of the gray lines connecting the proteins is proportional to the interaction score in the DPiM. Proteins belonging to individual clusters with GO term enrichment are shown with different colors. Proteins colored gray are part of clusters that are not enriched for any specific GO terms. Smn protein (indicated by an arrowhead) itself is connected to only Nmdmc and shown as an interacting pair at the bottom.