Table 7.
The risk of low CRH mRNA placenta content associated with low gestational age only, inflammation only, and both low gestational age and inflammation among pregnancies with spontaneous reasons for preterm delivery
| GA alone | Inflammation alone | GA and Inflammation | |
|---|---|---|---|
| Inflammation a | 1.9 (1.4–2.5) | 1.8 (1.3–2.4) | |
| GA 23–24 wk | 2.3 (1.6–3.4) | 2.2 (1.5–3.1) | |
| GA 25–26 wk | 1.3 (0.9–1.9) | 1.3 (0.9–1.8) |
Odds ratio (95% confidence Interval) for being in the lowest CRH quartile associated with inflammation and gestational age among infants delivered for preterm labor, pre-labor premature ruptured membranes, abruption, or cervical insufficiency. Infants delivered for maternal or fetal reasons have been excluded. Statistically significant elevated values are in bold. Abbreviation: GA, gestational age.
Inflammation of the chorion/decidua or chorionic plate, neutrophilic infiltration of the fetal stem vessels, and umbilical cord vasculitis