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. 2013 Jun 25;2(6):e101. doi: 10.1038/mtna.2013.27

Figure 4.

Figure 4

Neuronal transduction of CD-1 mouse brain on P22 after intracerebroventricular administration of rAAV9-GFP on E15. (a) Hippocampal, cortical, olfactory, and some cerebellar neurons demonstrate sustained GFP expression ~1 month after vector administration. (b) Immunohistochemical staining at P130 shows sustained transgene expression in the choroid plexus in the fourth ventricle (CP4) of CD-1 mouse brains, more than 4 months after intracerebroventricular administration on E15 with either rAAV5-GFP or rAAV9-GFP. Bars, 100 μm. GFP, green fluorescent protein; rAAV, recombinant adeno-associated virus.