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. 2013 Mar 15;30(6):441–452. doi: 10.1089/neu.2012.2622

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Copyright 2013, Mary Ann Liebert, Inc.

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FIG. 3. — Riluzole enhances tissue preservation following cervical SCI. Spinal cord cross-sections were stained serially with LFB/HE. Representative images taken from the injury epicenter of control (A) and P1 (B). Measurements of residual tissue taken from cross-sectional areas were expressed as a percent of the total cross-section area of the section (C). This experiment revealed a significant improvement in tissue preservation in the riluzole-treated groups. The percentage of remaining tissue was 50.74±6.41% in P1 and 35.99±3.30% in control at injury epicenter (p=0.014). At 400 μm caudal to the injury epicenter, the P1 group had significantly more preserved neural tissue (52.28±2.74%) compared to control (36.98±4.56%) (p=0.010).