Table 2. Comparison of the number of different viral taxa per sample at the species level between MetaVir and our tBLASTX approach, using unassembled and assembled reads.

Sample	Number of viral species
	MetVir								tBLASTX
	Unassembled				Assembled				Unassembled	Assembled
	10−3	10−5	10−7	50 on Score	10−3	10−5	10−7	50 on Score	10−3	10−3
C1	73	57	43	46	66	53	41	43	77	73
C2	222	178	151	156	203	168	141	148	272	240
C3	66	43	33	31	43	33	25	26	75	57
C4	159	117	92	104	108	87	70	80	190	149
C5	237	165	135	145	140	99	81	87	245	159
C6	156	85	61	69	63	39	29	35	203	76
C7	94	68	53	57	41	33	23	27	115	59
C8	247	166	141	146	131	99	77	86	298	141
C9	110	75	56	63	56	40	30	34	115	52
C10	68	45	34	37	37	26	21	22	61	44
IC1	31	19	8	11	18	9	6	8	39	19
V1	313	236	195	213	248	188	153	168	363	284
V2	353	285	244	263	209	167	146	155	376	217
V3	315	255	222	237	233	186	163	176	371	270
V4	146	101	85	95	101	80	68	75	145	89
V5	34	19	17	18	18	14	13	14	34	20
V6	297	218	182	190	256	194	159	169	380	316
V7	61	41	31	34	45	38	30	32	70	59
V8	118	81	67	68	94	73	60	62	137	113

Four thresholds (10⁻³, 10⁻⁵, and 10⁻⁷ on E value plus 50 on Score) are displayed by MetaVir using the raw reads number, whereas only the 10⁻³ on E value threshold is showed in our approach.

C1–C10, CD fecal samples; IC1, CD intestinal sample; V1–V8, control samples.