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. Author manuscript; available in PMC: 2014 Aug 29.
Published in final edited form as: Neuroscience. 2013 May 14;246:312–328. doi: 10.1016/j.neuroscience.2013.05.009

Table 1.

NE effects on the properties of both pre- and post-synaptic neurons

P-FS (n=7) FS-P (n=7) P-P (n=12)
Pre-NE Post-NE P value Pre-NE Post-NE P value Pre-NE Post-NE P value
Presynaptic Neuron
Resting membrane potential (mV) −67.9±2.04 −66.0±2.10 0.131 −70.0±1.74 −66.0±1.80 0.222 −65.7±5.10 −66.1±6.92 0.878
input resistance (MΩ) 112±16.3 118±22.3 0.572 200±31.6 211±38.8 0.50 135±48.9 137±38.8 0.820
Membrane time constant (ms) 29.5±3.15 28.0±3.26 0.640 7.55±1.36 8.70±1.99 0.221 26.5±1.33 25.0±1.55 0.303
AP threshold (mV) −44.2±1.88 −3.7±1.32 0.811 −5.2±1.12 −3.4±1.33 0.255 −2.6±1.23 −1.2±0.85 0.374
AP half-width (ms) 1.79±0.17 2.04±0.21 0.122 0.46±0.12 0.47±0.12 0.136 2.24±0.25 2.35±0.23 0.697
Postsynaptic neuron
inject current (pA) −17.5±16.2 −35.4±14.6 0.147 20.6±14.9 −2.8± 15.6 0.084 −6.17±12.1 −2.99±11.4 0.605
Latency (ms) 0.52±0.10 0.58±0.06 0.331 0.50±0.06 0.48±0.06 0.278 0.99±0.10 0.99±0.09 0.918
Amplitude (pA) 36.9±15.6 10.4±4.76 0.058 30.5±15.5 25.0±13.4 0.140 11.5±2.06 11.0±3.02 0.861
20–80% rise time (ms) 0.71±0.09 0.93±0.19 0.272 0.68±0.07 0.96±0.16 0.123 1.41±0.29 1.32±0.17 0.577
63% decay time (ms) 5.50±0.94 5.90±1.19 0.7196 8.23±0.85 10.2±1.55 0.0967 11.2±1.79 9.50±1.55 0.2649
Half-duration (ms) 5.81±1.10 5.88±0.87 0.9304 12.7±1.18 12.8±1.33 0.9411 10.8±1.80 10.7±1.72 0.8806