Table 4.

Forearm vascular resistance during norepinephrine (NE), adenosine (ADEN), and isoproterenol (ISO)

	Sildenafil	Placebo	P valuea
	% Change in FVR	% Change in FVR
NE
48 pmol/min	+24±7	+22±7	0.68
480 pmol/min	+64±15	+56±14
ADEN
30 mcg/min	−55±5	−56±5	0.67
300 mcg/min	−80±2	−78±2
ISO
25ng/min	−52±5	−50±4	0.47
250ng/min	−77±3	−72±3

Abbreviation: FVR, forearm vascular resistance.

^aAnalysis of variance: Group × dose interaction (group = sildenafil or placebo).