Table 4.
Antibacterial activities of compounds 2-10.
| IC50/MIC, μg/mL |
|||||
|---|---|---|---|---|---|
| Compound | S. aureus | MRS | E. coli | P. aureginosa | M. intracellulare |
| 2 | −/− | −/− | −/− | −/− | −/− |
| 3 | 1.35/5 | 1.47/2.5 | −/− | −/− | 11.9/− |
| 6 | 1.33/2.5 | 0.96/2.5 | −/− | −/− | 14.5/− |
| 7 | 1.75/5 | 1.56/2.5 | −/− | −/− | −/− |
| 8 | 6.8/20 | 8.44/20 | −/− | −/− | −/− |
| 9 | −/− | −/− | −/− | −/− | −/− |
| 10 | −/− | −/− | −/− | −/− | −/− |
| Ciprofloxacin | 0.1/0.25 | 0.08/0.25 | 0.004/0.008 | 0.06/0.25 | 0.30/1.00 |
=Not Active; NT = Not Tested; IC50 is the concentration that affords 50% inhibition of growth; MIC is the lowest test concentration that allows no detectable growth.