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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Psychol Med. 2012 Jul 18;43(4):813–823. doi: 10.1017/S0033291712001493

Table 4.

Results of Cox proportional hazards regression analyses predicting transition time from first drink to onset of first alcohol use disorder (AUD) symptoma

Base model
HR (95% CI)
Model with
Covariates
HR (95% CI)
Cannabis use 1.16 (0.96–1.40) 1.18 (1.00–1.38)
Order of initiationb
  Cannabis first 0.69 (0.57–0.84)* 0.68 (0.56–0.83)*
  Same age 0.79 (0.68–0.92)* 0.78 (0.66–0.91)*
  No cannabis 0.40 (0.34–0.47)* 0.45 (0.39–0.53)*
AA ethnicity 0.72 (0.60–0.86)* 0.74 (0.61–0.90)*
Maternal alcohol problems 1.17 (1.00–1.36) 1.03 (0.88–1.21)
Paternal alcohol problems 1.23 (1.09–1.39)* 1.09 (0.97–1.24)
Childhood physical abuse or neglect
(CPAN)
1.09 (0.95–1.25)
Childhood sexual abuse (CSA) 1.14 (0.97–1.33)
Major depressive disorder (MDD) 1.38 (1.22–1.55)*
Conduct disorder (CD) 1.47 (1.19–1.82)*
Regular smoking 1.22 (1.04–1.44)*

AA, African-American; HR, hazard ratio; CI, confidence interval.

a

Adjusted for age at time of symptom report, age at first use, sampling design, and proportional hazards violations.

b

Alcohol first as reference group.

*

p < 0.05.