Table 5.
Direct Interaction Effects | B (β) | SE | CI |
---|---|---|---|
Maltreatment to LSCL-33 | 0.005 (0.004) | 0.004 | [−0.002, 0.013] |
Haplotype to LSCL-33 | −0.485 (−0.405) | 0.343 | [−1.162, 0.180] |
GxE interaction to LSCL-33 | 0.014 (0.354) | 0.007 | [0.001, 0.027]* |
Maltreatment to BDI-II | 0.109 (0.011) | 0.043 | [0.027, 0.195]* |
Haplotype to BDI-II | 0.255 (0.026) | 2.924 | [−5.647, 5.838] |
GxE interaction to BDI-II | 0.015 (0.001) | 0.062 | [−0.105, 0.138] |
Maltreatment to DES | 0.004 (0.003) | 0.005 | [−0.006, 0.013] |
Haplotype to DES | −0.534 (−0.340) | 0.439 | [−1.388, 0.322] |
GxE interaction to DES | −0.012 (0.008) | 0.008 | [−0.003, 0.027] |
Conditional Indirect Effects | B (β) | SE | CI |
Maltreatment to BDI-II via LSCL-33 | |||
1 or 2 copies CATT haplotype | 0.056 (0.137) | 0.020 | [0.025, 0.105]** |
No copies of CATT haplotype | 0.015 (0.037) | 0.012 | [−0.007, 0.042] |
Difference | 0.041 (0.101) | 0.023 | [0.004, 0.095]* |
Maltreatment to DES via LSCL | |||
1 or 2 copies CATT haplotype | 0.010 (0.132) | 0.004 | [0.005, 0.019]** |
No copies of CATT haplotype | 0.003 (0.002) | 0.002 | [−0.001, 0.008] |
Difference | 0.008 (0.004) | 0.004 | [0.001, 0.017]* |
p<0.05
p<0.01
p<0.001.
SE = standard error of unstandardized path coefficients; CI = confidence interval of unstandardized path coefficients; FKBP5 haplotype coded as zero or 1–2 copies of CATT.