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. 2013 Jun 13;2013:851428. doi: 10.1155/2013/851428

Scheme 1.

Scheme 1

Proposed mechanism for folate-dependent conversion of L-serine to glycine, based on structural information, stereochemical studies, and properties of site mutants. B1H is believed to be Glu75 of eSHMT [28]. The other catalytic groups are not identified.