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. 2013 Jul;57(7):3182–3193. doi: 10.1128/AAC.00555-13

Table 4.

Allelic polymorphisms observed in MRR1 and ERG11 for C. albicans strains

Gene and isolate Allele (GenBank accession no.) Amino acid substitution(s)a
MRR1
    DSY291 Allele 1 (EU497754)
Allele 2 (EU497755) S16I, T73K, S171P, E1020Q, 2× NPQS
    JEY355 Allele MRR1V877F (KC676659) S16I, T73K, S171P, V877F, E1020Q, 2× NPQS
    JEY429 Allele MRR1V877F S16I, T73K, S171P, V877F, E1020Q, 2× NPQS
    JEY430 One allele 2 from DSY291 S16I, T73K, S171P, E1020Q, 2× NPQS
    JEY431 Two MRR1V877F alleles S16I, T73K, S171P, V877F, E1020Q, 2× NPQS
    JEY432 Two alleles 2 from DSY291 S16I, T73K, S171P, E1020Q, 2× NPQS
ERG11
    JEY355 Allele 1 (KC676660) E266D
Allele 2 (KC676661) D116E, E266D
a

–, Only amino acids that differ from those of Mrr1 of strain SC5314 are listed. The new gain-of-function mutation is indicated in boldface.