Fig 1.

Aggregation of lipid vesicles induced by HM1. DLS (top) and SLS (bottom) measurements were performed with 100 μM HM1 at pH 5.6 at RT in the presence of increasing concentrations of lipid SUVs composed of E. coli total lipid extract (a), POPC-POPG (3:1 [mol/mol]) (b), or POPE-POPG (3:1 [mol/mol]) (c) (circles). As controls, all vesicle concentrations were also measured in the absence of HM1 (squares). For DLS measurements, the data points indicate the medians of maximal and minimal particle sizes (error bars) out of 10 measurements. SLS data points are expressed as mean values of 10 measurements, with the error bars indicating the corresponding standard deviations. r_h, hydrodynamic radius.