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Aggregation of living bacteria by HM1. Depicted are micrographs of Gram-negative E. coli ATCC 25922 (top) and of Gram-positive Streptococcus pyogenes ATCC 12344 (bottom) in the absence (a and c) or presence (b and d) of sublethal dosages of HM-1 after 10 min of incubation. HM1 led to the formation of cell aggregates of both E. coli (b) and S. pyogenes (d), whereas untreated control samples showed a uniform distribution of bacterial cells.
