Fig 7.

Diminished/delayed parasitemia in mice caused by 1433-resistant T. brucei. (A) Control group: parasitemia of wild-type clones injected into mice at 5 × 10⁴ i.p. (C, clone; M, mouse). All mice were sacrificed by day 4 due to high parasitemia. (B) Parasitemia of 1433-resistant clones in the first pass in mice (infection dose, 5 × 10⁴ i.p.). (C) Parasitemia of wild-type clones in the second pass in mice (infection dose, 2 × 10⁴ i.p.). (D) Parasitemia of 1433-resistant clones in the second pass in mice (infection dose, 2 × 10⁴ i.p.). See Results for further explanation.