Table 3.
Multiple logistic regression analysis for the risk of major malformations among infants born to women exposed during the first trimester to macrolides vs the unexposed
| Variable | Major malformation OR (95% CI)a | P value |
|---|---|---|
| Macrolide exposure | 1.074 (0.839–1.376) | 0.57 |
| Maternal age | 1.019 (1.013–1.025) | <0.001 |
| Pregestational diabetes | 1.678 (1.370–2.055) | <0.001 |
| Parity | 0.959 (0.946–0.972) | <0.001 |
| Ethnicity (Bedouin/Jewish) | 1.453 (1.362–1.550) | <0.001 |
| Year of birth/pregnancy termination | 1.025 (1.017–1.033) | <0.001 |
a
OR, odds ratio; CI, confidence interval.