Table 5.
Categorical multiple logistic regression analysis for the effect of macrolide dose on the risk for major malformations
| Variable | Major malformation OR (95% CI)a | P value |
|---|---|---|
| DDDb | ||
| Unexposed | Reference | |
| 1–5 | 0.928 (0.287–2.999) | 0.9 |
| 6–10 | 1.095 (0.282–4.246) | 0.89 |
| >10 | 1.322 (0.365–4.790) | 0.78 |
| Maternal age (yr) | 1.019 (1.013–1.025) | <0.001 |
| Pregestational diabetes | 1.712 (1.398–2.097) | <0.001 |
| Parity | 0.959 (0.945–0.972) | <0.001 |
| Ethnicity (Bedouin/Jewish) | 1.451 (1.360–1.549) | <0.001 |
| Year of birth or pregnancy termination | 1.025 (1.017–1.033) | <0.001 |
a
OR, odds ratio; CI, confidence interval.
b
DDD, defined daily dose. For a description, see the text.