Fig 2.

(A) Comparison by spot assays of the susceptibilities of C. glabrata strains KUE100 and KUE100_Δcgqdr2 to miconazole, clotrimazole, ketoconazole, fluconazole, itraconazole, and quinidine, at the concentrations indicated, in BM agar plates. (B) Comparison by spot assays of the susceptibilities of C. glabrata strain L5U1, harboring the pGREG576 cloning vector (v) or the pGREG576_CgQDR2 plasmid, to miconazole, clotrimazole, ketoconazole, and quinidine, at the indicated concentrations, in BM agar plates. The inocula were prepared as described in Materials and Methods. The cell suspensions used to prepare the spots were 1:5 (b) and 1:25 (c) dilutions of the cell suspension used for column a. The images displayed are representative of at least three independent experiments.