Table 4.

IC₅₀s of synthetic quinolinium salts against Luc-tg L. major amastigotes, determined by the luminescence assay, and against BMDM, determined by the alamarBlue assay, and calculated SI

Compound	IC50 for:			SIa
	Amastigotes		BMDM, μM
	μM	μg/ml
1	0.05	0.05	>20	>400
18d	0.05	0.03	7.4	148
19d	0.03	0.01	2.30	76.7
21c	0.06	0.03	21.5	358
21d	0.04	0.02	2.80	70.0
22d	0.26	0.14	5.30	20.4
26d	0.04	0.02	1.49	37.3
27d	0.09	0.06	1.65	18.3

^aSI = IC₅₀ for BMDM/IC₅₀ for L. major.