Table 1.
Demographic, laboratory, hemodynamic, and intraoperative treatment dataa
| Parameter (unit) | CPB group (n = 5) | OPCAB group (n = 5) | P value |
|---|---|---|---|
| Sex (M/F) | 2/3 | 3/2 | |
| Body wt (kg) | 41.0 (35–42)/39.4 ± 1.2 | 38.0 (36–44)/39.4 ± 1.4 | 1.0 |
| Creatinine (mg/dl) | 0.9 (0.9–1.2)/0.95 ± 0.12 | 1.0 (0.7–1.3)/1.0 ± 0.2 | 0.55 |
| BUN (mg/dl) | 10 (8–12)/9.8 ± 2 | 8 (8–10)/8.8 ± 1.8 | 0.26 |
| Lactate max (mmol/liter) | 4.7 (3–6.2)/4.5 ± 1.6 | 3.5 (1.5–4.5)/3.0 ± 1.4 | 0.1 |
| CO (liter/min) | 5.8 (5.5–7.8)/6.2 ± 0.7 | 6.2 (5.1–7.0)/6.2 ± 0.5 | 0.97 |
| Svo2 (%) | 50 (40–60)/51 ± 7.2 | 62 (54–75)/63 ± 7.6 | 0.056 |
| Do2 (ml/min) | 734 (627–910)/756 ± 83.4 | 790 (700–960)/803 ± 90 | 0.25 |
| Vo2 (ml/min) | 245 (240–300)/250 ± 21.1 | 255 (235–311)/261 ± 18.9 | 0.73 |
| Sao2 (%) | 98 (95–99)/98 ± 1.5 | 98 (94–100)/98 ± 1.5 | 0.74 |
| Fluid balance (ml) | 2,050 (2,300–4,500)/2,010 ± 620 | 1,800 (1,050–1,850)/1,430 ± 250 | 0.06 |
| Norepinephrine intraop. (μg/kg/min) | 0.09 (0.06–0.2)/0.11 ± 0.04 | 0.02 (0–0.05)/0.02 ± 0.01 | 0.01a |
| Norepinephrine postop. (μg/kg/min) | 0.02 (0–0.1)/0.07 ± 0.02 | 0.01 (0–0.05)/0.01 ± 0.01 | 0.073 |
| Dobutamine (μg/kg/min) | 4 (2–5)/3.7 ± 0.9 | 0 (0–1)/0.2 ± 0.2 | <0.001a |
| Duration of surgery (min) | 210 (172–244)/196 ± 11.9 | 189 (139–215)/182 ± 15.6 | 0.79 |
| Albumin (g/dl) | 3.0 (2.8–3.2)/3.0 ± 0.3 | 3.2 (3.1–3.7)/3.3 ± 0.4 | 0.1 |
| Total protein (g/dl) | 5.1 (4.9–5.9)/5.3 ± 0.9 | 5.3 (4.7–5.7)/5.4 ± 0.8 | 0.82 |
| Protein binding of LVX (%) | 32.2 (30–35.9)/32.8 ± 1.4 | 36.8 (33.9–40.3)/37 ± 1.9 | 0.06 |
a
P values of <0.05 indicate a significant difference. Except for P values, values are given as median (range)/mean ± SD. Abbreviations: BUN, blood urea nitrogen; lactate max, intraoperative maximum value of lactate; CO, cardiac output; Svo2, mixed venous blood oxygen saturation; Do2, oxygen delivery; Vo2, oxygen consumption; Sao2, arterial blood oxygen saturation; intraop., intraoperative; postop., postoperative.