Table 1.
Performance statistics of the intramacrophage assay
| Performance statistic | Avg ± SD (n)a |
|---|---|
| Z-factor | 0.68 ± 0.09 (518) |
| %CV | 9.8 ± 2.8 (518) |
| S:B | 90 ± 51 (518) |
| Amphotericin B potency (pEC50) | 6.74 ± 0.18 (41) |
| % Infected cells | 81 (19,738) |
| Throughput | 20 × 384 wells per batch |
a
Values are averages ± the standard deviation except as noted otherwise in column 1. n is the number of plates for the Z-factor, the percent coefficient of variation (%CV), and the signal-to-background ratio (S:B), the number of curves for amphotericin B potency, and the number of cells for the percent infected cells.