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Effect of lipopolysaccharide (LPS) treatment on serum creatinine (A) and alanine aminotransferase (B) activities in wild-type (WT) and TRPV1-null mutant (TRPV1−/−) mice. Serum samples were collected at 24 h after intraperitoneal injection of vehicle or LPS (5 million endotoxin units/kg). Values are means ± SE (n = 6 to 8). *, P value of <0.05 compared with control WT or TRPV1−/− mice; †, P value of <0.05 compared with LPS-treated WT mice.
