Table 1.
Immunizing B. thailandensis strainb | % survival after challenge with B. pseudomallei at a dose (CFU) of: |
||
---|---|---|---|
6 × 104 | 6 × 105 | 6 × 106 | |
PBS (control) | 20 | 0 | 0 |
CDC2721121 | 100 | 100 | 20c |
E555 | 100 | 100 | 100 |
Survival at day 35 postchallenge (n = 5 mice for each group).
Immunizations via the i.p. route with ∼5 × 105 CFU per mouse.
The median time to death was significantly increased in this group compared to that in the PBS group (P = 0.0495).