Table 1.
ER stress induces changes in the Toxoplasma transcriptomea
| No. of Toxoplasma gene transcripts that are: |
P value | |||
|---|---|---|---|---|
| Activated |
Repressed |
|||
| >1-fold | ≥2.0-fold | <1.0-fold | ≤0.5-fold | |
| 710 | 305 | 7,347 | 3,493 | |
| 136 | 121 | 5,546 | 3,169 | ≤0.05 |
| 58 | 55 | 4,136 | 2,654 | ≤0.01 |
a
Shown are the number of Toxoplasma gene transcripts that are activated or repressed in parasites subjected to ER stress by treatment with tunicamycin for 1 h. Changes in transcript levels were assayed using three biological replicates and were analyzed for statistical significance as the means ± standard errors (SE). Data were statistically significant according to P value (<0.05 or 0.01, as indicated). A total of 8,057 probe sets were analyzed.